Paul Garcia, MD, PhD

Associate Professor; Chief, Neuroanesthesia Division

Research Description

Dr. Garcia's research has focused on neurophysiology (including human/rodent EEG and patch-clamp electrophysiology) and behavioral testing in animal models. His translational laboratory research focuses on models of neuronal degeneration caused by age, anesthesia, or other pharmacologic exposure. He has transitioned some of this research into the human/clinical realm. His clinical research projects involve investigating intraoperative EEG signatures and their association with adverse postoperative outcomes. Early recognition of cognitive problems can aid in preventing an escalation of clinical acuity and bring down hospital costs. Specific sequences observed in frontal EEG during emergence from general anesthesia are associated with pain and delirium in the recovery room. Understanding the generation of these signals can lead to improved care for patients in the care of anesthesiologists.