Guang Yang, PhD

Associate Professor of Anesthesiological Sciences

Research Description

The brain is segregated from the rest of the body via the blood-brain barrier and has long been considered as an immune privileged organ. Recently, this view has shifted with increasing evidence showing a complex reciprocal relationship between the immune and nervous systems in health and disease. My laboratory studies how immune cells, anesthetics and sleep regulate changes in neural circuits that are important for sensory processing and memory formation. We focus on the mechanisms by which pathological immune responses contribute to neurological disorders including chronic pain, postoperative cognitive dysfunction, and Alzheimer’s disease.  The laboratory uses a combination of techniques including in vivo two-photon imaging, molecular manipulation, biochemistry and behavioral analysis to address these questions.

For more information, please contact Dr. Yang at gy2268@cumc.columbia.edu

Members

  • Linlin Sun, PhD

    Postdoctoral Research Scientist

  • Hang Zhou, PhD

    Postdoctoral Research Scientist

Select Publications

View a complete list of Dr. Yang's publications.