George Hasko, MD, PhD
Professor of Anesthesiological Sciences (in Anesthesiology)
Dr. Hasko’s research is centered on the role of P1 (adenosine) and P2 (ATP) purinergic receptors in regulating inflammation and organ function in sepsis. He uses state-of-the-art techniques, such as the "cre-lox” technology to delineate the role purinergic receptors on the various cell types that are involved in orchestrating the host's inflammatory response to sepsis. In mechanistic in vitro studies, his research aims to clarify the molecular processes underpinning the purinergic regulation of inflammation and he is especially interested in cells of the innate immune system, such as macrophages and innate lymphoid cells. In addition, he is interested in how purinergic receptors regulate inflammation, organ injury and immunity to intestinal worms.